Early access · Spring 2026
New York · Incorporated in Delaware
Clinical companion for GLP-1 therapy

A companion for the
thirty million Americans
on GLP‑1 therapy.

Built for the week six plateau, the cost and coverage gap, and the long arc of adherence after the first injection.

30M Americans on GLP-1 therapy, 2026
W6–12 Plateau window we address
8.1% Three-year class persistence
app.glp1ai.com / dashboard
Week 14 · on track N. Lee · Case 0142

You are 2.4 points ahead of the STEP-1 curve.

PLATEAU
Your trajectory STEP-1 expected Plateau window
Current
−30.8lb
Vs. STEP-1
+2.4pt
Confidence
92%
Built on the molecules millions already trust
Semaglutide
Tirzepatide
Liraglutide
Retatrutide
Orforglipron
The real failure mode

Users don’t stop because the drug fails. They stop because the infrastructure around it does.

Discontinuation rarely comes from the molecule. It comes from the plateau no one warned them about, the coverage letter that never arrived, and the transition no one mapped when compounded supply ended. Four numbers describe the gap.

01 / 04
47.6%
Cost, insurance, or access is the primary reason cited by users who discontinue GLP-1 therapy.
Cleveland Clinic
Obesity, 2026 · N=288
02 / 04
W6–12
Plateau window — when weight loss stalls, side effects compound, and prescribers say "wait."
BERTopic analysis
46,491 posts · 2024
03 / 04
1.5M+
Compounded semaglutide users left without a transition path after the February 2026 shutdown.
CNBC, Feb 9 2026
Novo Nordisk data
04 / 04
8.1%
Three-year persistence across the GLP-1 class. Most users are off therapy within 24 months.
Prime Therapeutics
N=5,780
What we built

A clinical companion for the full arc of treatment — from first injection to maintenance.

Three connected modules. One continuous system. Built mobile-first for patients, institutionally-rigorous for partners.
Module 01

Plateau Predictor

A decision engine built for the week six-to-twelve window. When the scale stops moving, the companion knows what to suggest next.

HRVWeight ΔSleepHunger
Module 02

Integrated log

Injection timing, biometrics, symptoms, and nutrition in one place. Connects the dose day to the symptom day — structured for clinical use.

InjectionSymptomsMealsWeight
Module 03

Community by week

Peer support anonymized by week of therapy, not by name. Protocol-specific nuance without social stigma or identity risk.

W1–4W5–12W13–24Maintenance
&

Access navigation for cost and coverage. Medication transition guidance for users moving off compounded therapy. Scheduled wellbeing check-ins at weeks four, eight, and twelve.

The market has decided

Persistence is rising. Majors are partnering. Regulators are moving.

Four signalsTwelve-month window
Q2 2025 — Q1 2026
Persistence01
60.9%
Up from 24.5% in the 2021 cohort
One-year persistence in the 2024 semaglutide cohort — a 2.5× improvement driven by supply and coverage stabilization.
Prime Therapeutics
JMCP · March 2026
Majors02
$40B+
Novo & Lilly FY24 incretin revenue
Neither major is building a proprietary digital companion. Both have moved toward external partnership models.
Sidekick × Lilly
Novo × Hims · 03/09/26
FDA03
3 signals
All within twelve months
Device RWE guidance finalized Dec 2025. CDS guidance revised Jan 6 2026. SI/B warnings formally removed Jan 13 2026.
Federal Register
FDA guidance documents
RWE exits04
$2.7B+
Disclosed deal value
Tempus × AstraZeneca $200M. Roche × Flatiron $1.9B. Datavant × Aetion $400M. ResMed × Propeller $225M.
Public M&A filings
2018 — 2025
The window we address

The plateau is predictable. The support for it is not.

STEP-1 trajectorybaseline
With companionmodeled
Post-discontinuationSTEP-4
Plateau windowW6 — 12

Trajectory with vs. without companion

% weight loss · weeks 0 to 24 STEP-1 aligned · N = 1,961
0% −4% −8% −12% −15% W0 W4 W8 W12 W16 W20 W24 PLATEAU WINDOW · W6 — 12 Regained after discontinuation TYPICAL DISCONTINUATION Week 8 · ~47.6% cite access STEP-1 baseline · −9% With companion · −13% +4pt

Two-thirds of weight lost on therapy is regained within one year of discontinuation (STEP-4). The companion stays with the user across the full arc — from the first injection, through the plateau window, and into maintenance.

STEP-1 aligned model
N = 1,961
Where this goes next

Join the waitlist.

Built for users on semaglutide, tirzepatide, and the next wave of incretins. One email when access opens. No marketing, no list swaps.

Clinical companion. Not a substitute for medical advice.
For pharma

Partner with evidence.

CDISC-compliant data architecture, Expert Determination de-identification, tiered partner access.

Contact partnerships
For prescribers

Users arrive prepared.

Structured intake, decision support under the revised January 2026 FDA CDS framework.

For clinicians
For investors

Diligence-ready pack.

Deck, supporting RWE analysis, and market sizing model available under mutual NDA.

Request the deck